Urocortin
Urocortin

Urocortin

2RMF, 3N967349n/aENSG00000163794n/aP55089n/aNM_003353n/aNP_003344n/aUrocortin là một loại protein ở người được mã hóa bởi gen UCN. Urocortin thuộc họ protein giải phóng corticotropin (CRF) bao gồm CRF, urotensin I, sauvagine, urocortin II và urocortin III. Urocortin có liên quan đến phản ứng căng thẳng của động vật có vú và điều chỉnh các khía cạnh của sự thèm ăn và phản ứng stress.[2][3][4]

Urocortin

Quá trình sinh học positive regulation of collagen biosynthetic process
G-protein coupled receptor signaling pathway
negative regulation of histone deacetylation
activation of protein kinase A activity
response to estradiol
positive regulation of protein phosphorylation
associative learning
Phản ứng giật mình
gastric emptying
negative regulation of blood pressure
female pregnancy
negative regulation of gastric acid secretion
negative regulation of apoptotic process
response to glucocorticoid
sensory perception of sound
pancreatic juice secretion
response to oxidative stress
negative regulation of appetite
positive regulation of translation
negative regulation of gene expression
negative regulation of cell death
positive regulation of peptidyl-serine phosphorylation
positive regulation of DNA replication
aerobic respiration
positive regulation of calcium ion import
positive regulation of cell growth
positive regulation of vascular permeability
positive regulation of gene expression
drinking behavior
response to pain
positive regulation of cardiac muscle contraction
tập tính ăn ở động vật
positive regulation of interleukin-6 production
response to auditory stimulus
learning or memory
hành vi xã hội
regulation of synaptic transmission, glutamatergic
inflammatory response
neuropeptide signaling pathway
neuron projection development
negative regulation of necrotic cell death
positive regulation of behavioral fear response
negative regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
negative regulation of neuron death
negative regulation of hormone secretion
positive regulation of blood vessel diameter
negative regulation of feeding behavior
regulation of receptor activity
positive regulation of cAMP-mediated signaling
positive regulation of corticotropin secretion
negative regulation of epinephrine secretion
positive regulation of cortisol secretion
negative regulation of glucagon secretion
UniProt

P55089

Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học
Bản thể gen
Chức năng phân tửhistone deacetylase inhibitor activity
hormone activity
GO:0001948 protein binding
neuropeptide hormone activity
G-protein coupled receptor binding
corticotropin-releasing hormone receptor 1 binding
corticotropin-releasing hormone receptor 2 binding
corticotropin-releasing hormone activity
Thành phần tế bàoaxon terminus
soma
varicosity
sợi trục
sợi nhánh
neuronal cell body
extracellular region
extracellular
Quá trình sinh họcpositive regulation of collagen biosynthetic process
G-protein coupled receptor signaling pathway
negative regulation of histone deacetylation
activation of protein kinase A activity
response to estradiol
positive regulation of protein phosphorylation
associative learning
Phản ứng giật mình
gastric emptying
negative regulation of blood pressure
female pregnancy
negative regulation of gastric acid secretion
negative regulation of apoptotic process
response to glucocorticoid
sensory perception of sound
pancreatic juice secretion
response to oxidative stress
negative regulation of appetite
positive regulation of translation
negative regulation of gene expression
negative regulation of cell death
positive regulation of peptidyl-serine phosphorylation
positive regulation of DNA replication
aerobic respiration
positive regulation of calcium ion import
positive regulation of cell growth
positive regulation of vascular permeability
positive regulation of gene expression
drinking behavior
response to pain
positive regulation of cardiac muscle contraction
tập tính ăn ở động vật
positive regulation of interleukin-6 production
response to auditory stimulus
learning or memory
hành vi xã hội
regulation of synaptic transmission, glutamatergic
inflammatory response
neuropeptide signaling pathway
neuron projection development
negative regulation of necrotic cell death
positive regulation of behavioral fear response
negative regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
negative regulation of neuron death
negative regulation of hormone secretion
positive regulation of blood vessel diameter
negative regulation of feeding behavior
regulation of receptor activity
positive regulation of cAMP-mediated signaling
positive regulation of corticotropin secretion
negative regulation of epinephrine secretion
positive regulation of cortisol secretion
negative regulation of glucagon secretion
Nguồn: Amigo / QuickGO
Chức năng phân tử histone deacetylase inhibitor activity
hormone activity
GO:0001948 protein binding
neuropeptide hormone activity
G-protein coupled receptor binding
corticotropin-releasing hormone receptor 1 binding
corticotropin-releasing hormone receptor 2 binding
corticotropin-releasing hormone activity
Loài Người
RefSeq (protein)

NP_003344

RefSeq (mRNA)

NM_003353

Danh pháp UCN, UI, UROC, urocortin
ID ngoài OMIM: 600945 HomoloGene: 2515 GeneCards: UCN
PubMed [1]
PDB Tìm trên Human UniProt: PDBe RCSB
Thành phần tế bào axon terminus
soma
varicosity
sợi trục
sợi nhánh
neuronal cell body
extracellular region
extracellular
Danh sách mã id PDB
Danh sách mã id PDB

2RMF, 3N96

Ensembl

ENSG00000163794

Vị trí gen (UCSC) n/a
Entrez

7349

Cấu trúc được biết đếnPDBDanh sách mã id PDB
Cấu trúc được biết đến
PDBTìm trên Human UniProt: PDBe RCSB
Danh sách mã id PDB

2RMF, 3N96