Interleukin

Interleukin_2

Mẫu hình biểu hiện RNA

Mẫu hình biểu hiện RNA

Thêm nguồn tham khảo về sự biểu hiện

Quá trình sinh học

UniProt


P60568

Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học

Bản thể gen
Chức năng phân tử	• cytokine activity • interleukin-2 receptor binding • glycosphingolipid binding • kinase activator activity • growth factor activity • kappa-type opioid receptor binding • carbohydrate binding • GO:0001948 protein binding
Thành phần tế bào	• extracellular region • Nội bào • extracellular space
Quá trình sinh học	• positive regulation of T cell differentiation • negative regulation of protein phosphorylation • G protein-coupled receptor signaling pathway • positive regulation of protein phosphorylation • positive regulation of inflammatory response • adaptive immune response • negative regulation of heart contraction • immune system process • positive regulation of cytosolic calcium ion concentration • positive regulation of regulatory T cell differentiation • cell-cell signaling • positive regulation of interferon-gamma production • natural killer cell activation • negative regulation of apoptotic process • positive regulation of dendritic spine development • negative regulation of lymphocyte proliferation • MAPK cascade • regulation of T cell homeostatic proliferation • T cell differentiation • positive regulation of cell growth • protein kinase C-activating G protein-coupled receptor signaling pathway • cell adhesion • positive regulation of B cell proliferation • positive regulation of tissue remodeling • positive regulation of T cell proliferation • Phản ứng miễn dịch • positive regulation of cell population proliferation • extrinsic apoptotic signaling pathway in absence of ligand • negative regulation of B cell apoptotic process • positive regulation of isotype switching to IgG isotypes • positive regulation of interleukin-17 production • response to ethanol • negative regulation of inflammatory response • positive regulation of transcription by RNA polymerase II • positive regulation of activated T cell proliferation • negative regulation of T-helper 17 cell differentiation • leukocyte activation involved in immune response • positive regulation of tyrosine phosphorylation of STAT protein • regulation of regulatory T cell differentiation • regulation of signaling receptor activity • cytokine-mediated signaling pathway • interleukin-2-mediated signaling pathway • positive regulation of kinase activity
Nguồn: Amigo / QuickGO

Kết thúc

122,456,725 bp [1]

RefSeq (protein)


NP_000577

Loài

Người

Chức năng phân tử

• cytokine activity
• interleukin-2 receptor binding
• glycosphingolipid binding
• kinase activator activity
• growth factor activity
• kappa-type opioid receptor binding
• carbohydrate binding
• GO:0001948 protein binding

Danh pháp

IL2, IL-2, TCGF, lymphokine, interleukin 2

RefSeq (mRNA)


NM_000586

PubMed

[2]

ID ngoài

OMIM: 147680 HomoloGene: 488 GeneCards: IL2

NST

Nhiễm sắc thể 4 (người)[1]

PDB

Tìm trên Human UniProt: PDBe RCSB

Thành phần tế bào

• extracellular region
• Nội bào
• extracellular space

Vị trí gen (Người)NSTBăngBắt đầuKết thúc

Vị trí gen (Người)

NST	Nhiễm sắc thể 4 (người)[1]

Băng	4q27	Bắt đầu	122,451,470 bp [1]
Kết thúc	122,456,725 bp [1]

Danh sách mã id PDB

Danh sách mã id PDB
1IRL, 1M47, 1M48, 1M49, 1M4A, 1M4B, 1M4C, 1NBP, 1PW6, 1PY2, 1QVN, 1Z92, 2B5I, 2ERJ, 3QAZ, 3QB1, 3INK, 4NEJ, 4NEM

BăngBắt đầu

4q27

Ensembl


ENSG00000109471

Vị trí gen (UCSC)

Chr 4: 122.45 – 122.46 Mb

Entrez


3558

Cấu trúc được biết đếnPDBDanh sách mã id PDB

Cấu trúc được biết đến

PDB

Tìm trên Human UniProt: PDBe RCSB

Danh sách mã id PDB
1IRL, 1M47, 1M48, 1M49, 1M4A, 1M4B, 1M4C, 1NBP, 1PW6, 1PY2, 1QVN, 1Z92, 2B5I, 2ERJ, 3QAZ, 3QB1, 3INK, 4NEJ, 4NEM