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EXOSC10

Quá trình sinh học	• RNA processing • nuclear polyadenylation-dependent rRNA catabolic process • nucleic acid phosphodiester bond hydrolysis • nuclear retention of unspliced pre-mRNA at the site of transcription • CUT catabolic process • nuclear-transcribed mRNA catabolic process • nuclear mRNA surveillance • cell metabolism • maturation of 5.8S rRNA • histone mRNA catabolic process • dosage compensation by inactivation of X chromosome • nucleobase-containing compound metabolic process • rRNA processing • RNA phosphodiester bond hydrolysis, exonucleolytic • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • negative regulation of telomere maintenance via telomerase • regulation of telomerase RNA localization to Cajal body • exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • nuclear polyadenylation-dependent snoRNA catabolic process • nuclear polyadenylation-dependent snRNA catabolic process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent CUT catabolic process • nuclear polyadenylation-dependent antisense transcript catabolic process • polyadenylation-dependent snoRNA 3'-end processing
Mẫu hình biểu hiện RNA	Mẫu hình biểu hiện RNA Thêm nguồn tham khảo về sự biểu hiện
UniProt	Q01780
Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học	Bản thể gen Chức năng phân tử • nucleotide binding • exoribonuclease activity • GO:0001948 protein binding • catalytic activity • 3'-5' exonuclease activity • nucleic acid binding • nuclease activity • exonuclease activity • hydrolase activity • RNA binding • 3'-5'-exoribonuclease activity • telomerase RNA binding • single-stranded RNA binding Thành phần tế bào • Tế bào chất • exosome complex • membrane • nuclear exosome (RNase complex) • Nội bào • Hạch nhân • transcriptionally active chromatin • nhân tế bào • Chất nhân • cytosol Quá trình sinh học • RNA processing • nuclear polyadenylation-dependent rRNA catabolic process • nucleic acid phosphodiester bond hydrolysis • nuclear retention of unspliced pre-mRNA at the site of transcription • CUT catabolic process • nuclear-transcribed mRNA catabolic process • nuclear mRNA surveillance • cell metabolism • maturation of 5.8S rRNA • histone mRNA catabolic process • dosage compensation by inactivation of X chromosome • nucleobase-containing compound metabolic process • rRNA processing • RNA phosphodiester bond hydrolysis, exonucleolytic • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • negative regulation of telomere maintenance via telomerase • regulation of telomerase RNA localization to Cajal body • exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • nuclear polyadenylation-dependent snoRNA catabolic process • nuclear polyadenylation-dependent snRNA catabolic process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent CUT catabolic process • nuclear polyadenylation-dependent antisense transcript catabolic process • polyadenylation-dependent snoRNA 3'-end processing Nguồn: Amigo / QuickGO
Loài	Người
RefSeq (protein)	NP_001001998 NP_002676
Chức năng phân tử	• nucleotide binding • exoribonuclease activity • GO:0001948 protein binding • catalytic activity • 3'-5' exonuclease activity • nucleic acid binding • nuclease activity • exonuclease activity • hydrolase activity • RNA binding • 3'-5'-exoribonuclease activity • telomerase RNA binding • single-stranded RNA binding
RefSeq (mRNA)	NM_001001998 NM_002685
Danh pháp	EXOSC10, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4, exosome component 10
PubMed	[1]
ID ngoài	OMIM: 605960 HomoloGene: 31105 GeneCards: EXOSC10
PDB	Tìm trên Human UniProt: PDBe RCSB
Thành phần tế bào	• Tế bào chất • exosome complex • membrane • nuclear exosome (RNase complex) • Nội bào • Hạch nhân • transcriptionally active chromatin • nhân tế bào • Chất nhân • cytosol
Danh sách mã id PDB	Danh sách mã id PDB 2CPR, 3SAF, 3SAG, 3SAH
Ensembl	ENSG00000171824
Entrez	5394
Vị trí gen (UCSC)	n/a
Cấu trúc được biết đếnPDBDanh sách mã id PDB	Cấu trúc được biết đến PDB Tìm trên Human UniProt: PDBe RCSB Danh sách mã id PDB 2CPR, 3SAF, 3SAG, 3SAH

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EXOSC10 Tham khảo Đọc thêm

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EXOSC10

Tài liệu tham khảo

WikiPedia: EXOSC10 //pubmed.ncbi.nlm.nih.gov/10465791 //pubmed.ncbi.nlm.nih.gov/11110791 //pubmed.ncbi.nlm.nih.gov/11426320 //pubmed.ncbi.nlm.nih.gov/11719186 //pubmed.ncbi.nlm.nih.gov/11812149 //pubmed.ncbi.nlm.nih.gov/11879549 //pubmed.ncbi.nlm.nih.gov/12419256 //pubmed.ncbi.nlm.nih.gov/12429849 //pubmed.ncbi.nlm.nih.gov/12477932 //pubmed.ncbi.nlm.nih.gov/12788944