DVL1 Quá trình sinh học • regulation of protein phosphorylation• negative regulation of protein phosphorylation• regulation of neurotransmitter levels• positive regulation of protein phosphorylation• GO:0007243 intracellular signal transduction• axonogenesis• negative regulation of protein kinase activity• dendrite morphogenesis• synapse organization• protein stabilization• regulation of cellular protein localization• Đường truyền tín hiệu WNT• transcription by RNA polymerase II• negative regulation of protein binding• receptor clustering• planar cell polarity pathway involved in neural tube closure• axon guidance• positive regulation of transcription, DNA-templated• positive regulation of Wnt signaling pathway• multicellular organism development• Wnt signaling pathway, planar cell polarity pathway• protein localization to microtubule• neuromuscular junction development• cochlea morphogenesis• neural tube development• cytoplasmic microtubule organization• positive regulation of neuron projection development• axon extension• protein localization to nucleus• canonical Wnt signaling pathway• hành vi xã hội• skeletal muscle acetylcholine-gated channel clustering• collateral sprouting• convergent extension involved in neural plate elongation• negative regulation of canonical Wnt signaling pathway• GO:0010554 neurotransmitter secretion• positive regulation of proteasomal ubiquitin-dependent protein catabolic process• convergent extension involved in organogenesis• prepulse inhibition• positive regulation of canonical Wnt signaling pathway• beta-catenin destruction complex disassembly• dendritic spine morphogenesis• positive regulation of excitatory postsynaptic potential• presynapse assembly• positive regulation of protein localization to presynapse• non-canonical Wnt signaling pathway• postsynapse organization• positive regulation of neuron projection arborization• regulation of synaptic vesicle exocytosis UniProt O14640 Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học Bản thể genChức năng phân tử• beta-catenin binding• GO:0005110 frizzled binding• GO:0001948 protein binding• identical protein binding• enzyme binding• protein kinase bindingThành phần tế bào• Tế bào chất• cytosol• Wnt signalosome• lateral plasma membrane• membrane• microtubule cytoskeleton• growth cone• Màng tế bào• Xynap• sợi trục• neuronal cell body• sợi nhánh• neuron projection• Vi ống• clathrin-coated vesicle• presynapse• dendritic spine• GO:0097483, GO:0097481 postsynaptic density• GO:0016023 cytoplasmic vesicle• Schaffer collateral - CA1 synapse• glutamatergic synapseQuá trình sinh học• regulation of protein phosphorylation• negative regulation of protein phosphorylation• regulation of neurotransmitter levels• positive regulation of protein phosphorylation• GO:0007243 intracellular signal transduction• axonogenesis• negative regulation of protein kinase activity• dendrite morphogenesis• synapse organization• protein stabilization• regulation of cellular protein localization• Đường truyền tín hiệu WNT• transcription by RNA polymerase II• negative regulation of protein binding• receptor clustering• planar cell polarity pathway involved in neural tube closure• axon guidance• positive regulation of transcription, DNA-templated• positive regulation of Wnt signaling pathway• multicellular organism development• Wnt signaling pathway, planar cell polarity pathway• protein localization to microtubule• neuromuscular junction development• cochlea morphogenesis• neural tube development• cytoplasmic microtubule organization• positive regulation of neuron projection development• axon extension• protein localization to nucleus• canonical Wnt signaling pathway• hành vi xã hội• skeletal muscle acetylcholine-gated channel clustering• collateral sprouting• convergent extension involved in neural plate elongation• negative regulation of canonical Wnt signaling pathway• GO:0010554 neurotransmitter secretion• positive regulation of proteasomal ubiquitin-dependent protein catabolic process• convergent extension involved in organogenesis• prepulse inhibition• positive regulation of canonical Wnt signaling pathway• beta-catenin destruction complex disassembly• dendritic spine morphogenesis• positive regulation of excitatory postsynaptic potential• presynapse assembly• positive regulation of protein localization to presynapse• non-canonical Wnt signaling pathway• postsynapse organization• positive regulation of neuron projection arborization• regulation of synaptic vesicle exocytosisNguồn: Amigo / QuickGO Chức năng phân tử • beta-catenin binding• GO:0005110 frizzled binding• GO:0001948 protein binding• identical protein binding• enzyme binding• protein kinase binding RefSeq (protein) NP_001317240NP_004412 Loài Người RefSeq (mRNA) NM_004421NM_181870NM_182779NM_001330311 Danh pháp DVL1, DVL, DVL1L1, DVL1P1, DRS2, dishevelled segment polarity protein 1 PubMed [1] ID ngoài OMIM: 601365 HomoloGene: 20926 GeneCards: DVL1 PDB Tìm trên Human UniProt: PDBe RCSB Thành phần tế bào • Tế bào chất• cytosol• Wnt signalosome• lateral plasma membrane• membrane• microtubule cytoskeleton• growth cone• Màng tế bào• Xynap• sợi trục• neuronal cell body• sợi nhánh• neuron projection• Vi ống• clathrin-coated vesicle• presynapse• dendritic spine• GO:0097483, GO:0097481 postsynaptic density• GO:0016023 cytoplasmic vesicle• Schaffer collateral - CA1 synapse• glutamatergic synapse Danh sách mã id PDB Danh sách mã id PDB1FSH, 1MC7, 2KAW, 3PZ8 Ensembl ENSG00000107404 Vị trí gen (UCSC) n/a Entrez 1855 Cấu trúc được biết đếnPDBDanh sách mã id PDB Cấu trúc được biết đếnPDBTìm trên Human UniProt: PDBe RCSB Danh sách mã id PDB1FSH, 1MC7, 2KAW, 3PZ8
Tài liệu tham khảo WikiPedia: DVL1 //pubmed.ncbi.nlm.nih.gov/10330181 //pubmed.ncbi.nlm.nih.gov/10330403 //pubmed.ncbi.nlm.nih.gov/10428961 //pubmed.ncbi.nlm.nih.gov/10581192 //pubmed.ncbi.nlm.nih.gov/10644691 //pubmed.ncbi.nlm.nih.gov/10806215 //pubmed.ncbi.nlm.nih.gov/11113207 //pubmed.ncbi.nlm.nih.gov/11487578 //pubmed.ncbi.nlm.nih.gov/11742073 //pubmed.ncbi.nlm.nih.gov/11779461
