CDC73

Quá trình sinh học

• histone monoubiquitination
• regulation of transcription, DNA-templated
• positive regulation of mRNA 3'-end processing
• histone modification
• negative regulation of transcription from RNA polymerase II promoter
• Đường truyền tín hiệu WNT
• transcription, DNA-templated
• stem cell population maintenance
• negative regulation of G1/S transition of mitotic cell cycle
• positive regulation of Wnt signaling pathway
• mRNA polyadenylation
• endodermal cell fate commitment
• protein destabilization
• negative regulation of epithelial cell proliferation
• Chu kỳ tế bào
• histone H2B ubiquitination
• cellular response to lipopolysaccharide
• negative regulation of myeloid cell differentiation
• negative regulation of fibroblast proliferation
• positive regulation of transcription elongation from RNA polymerase II promoter
• negative regulation of cell proliferation
• positive regulation of transcription from RNA polymerase II promoter
• beta-catenin-TCF complex assembly
• regulation of cell growth
• regulation of transcription from RNA polymerase II promoter
• transcription from RNA polymerase II promoter
• transcription elongation from RNA polymerase II promoter
• protein ubiquitination
• recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
• negative regulation of apoptotic process
• positive regulation of cell cycle G1/S phase transition

UniProt


Q6P1J9

Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học

Bản thể gen
Chức năng phân tử	• RNA polymerase II core binding • GO:0001948 protein binding
Thành phần tế bào	• Chất nhân • Cdc73/Paf1 complex • nuclear chromosome, telomeric region • nhân tế bào • cytosol
Quá trình sinh học	• histone monoubiquitination • regulation of transcription, DNA-templated • positive regulation of mRNA 3'-end processing • histone modification • negative regulation of transcription from RNA polymerase II promoter • Đường truyền tín hiệu WNT • transcription, DNA-templated • stem cell population maintenance • negative regulation of G1/S transition of mitotic cell cycle • positive regulation of Wnt signaling pathway • mRNA polyadenylation • endodermal cell fate commitment • protein destabilization • negative regulation of epithelial cell proliferation • Chu kỳ tế bào • histone H2B ubiquitination • cellular response to lipopolysaccharide • negative regulation of myeloid cell differentiation • negative regulation of fibroblast proliferation • positive regulation of transcription elongation from RNA polymerase II promoter • negative regulation of cell proliferation • positive regulation of transcription from RNA polymerase II promoter • beta-catenin-TCF complex assembly • regulation of cell growth • regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter • transcription elongation from RNA polymerase II promoter • protein ubiquitination • recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex • negative regulation of apoptotic process • positive regulation of cell cycle G1/S phase transition
Nguồn: Amigo / QuickGO

Loài

Người

Chức năng phân tử

• RNA polymerase II core binding
• GO:0001948 protein binding

RefSeq (protein)


NP_078805

Danh pháp

CDC73, C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX, cell division cycle 73

RefSeq (mRNA)


NM_024529

PubMed

[1]

ID ngoài

OMIM: 607393 HomoloGene: 11571 GeneCards: CDC73

Thành phần tế bào

• Chất nhân
• Cdc73/Paf1 complex
• nuclear chromosome, telomeric region
• nhân tế bào
• cytosol

Ensembl


ENSG00000134371

Vị trí gen (UCSC)

n/a

Entrez


79577